An in vitro and in vivo evaluation of autologous platelet concentrate in oral reconstruction.
Identifieur interne : 007D47 ( Main/Exploration ); précédent : 007D46; suivant : 007D48An in vitro and in vivo evaluation of autologous platelet concentrate in oral reconstruction.
Auteurs : Charles A. Babbush [États-Unis] ; Sherwin V. Kevy ; May S. JacobsonSource :
- Implant dentistry [ 1056-6163 ] ; 2003.
Descripteurs français
- KwdFr :
- Activation plaquettaire, Adulte, Adulte d'âge moyen, Agrégation plaquettaire, Femelle, Humains, Implants dentaires, Mâchoire (), Mâchoire partiellement édentée (), Mâle, Numération des plaquettes, Pose d'implant dentaire endo-osseux, Reconstruction de crête alvéolaire, Solution hypotonique, Substances de croissance (analyse), Survie cellulaire, Sélectine P (analyse), Thrombocytaphérèse (), Thrombocytaphérèse (instrumentation), Transfusion de plaquettes (), Transfusion sanguine autologue.
- MESH :
- analyse : Substances de croissance, Sélectine P.
- Activation plaquettaire, Adulte, Adulte d'âge moyen, Agrégation plaquettaire, Femelle, Humains, Implants dentaires, Mâchoire, Mâchoire partiellement édentée, Mâle, Numération des plaquettes, Pose d'implant dentaire endo-osseux, Reconstruction de crête alvéolaire, Solution hypotonique, Survie cellulaire, Thrombocytaphérèse, Transfusion de plaquettes, Transfusion sanguine autologue.
English descriptors
- KwdEn :
- Adult, Alveolar Ridge Augmentation, Blood Transfusion, Autologous, Cell Survival, Dental Implantation, Endosseous, Dental Implants, Female, Growth Substances (analysis), Humans, Hypotonic Solutions, Jaw (surgery), Jaw, Edentulous, Partially (surgery), Male, Middle Aged, P-Selectin (analysis), Platelet Activation, Platelet Aggregation, Platelet Count, Platelet Transfusion (methods), Plateletpheresis (instrumentation), Plateletpheresis (methods).
- MESH :
- chemical , analysis : Growth Substances, P-Selectin.
- chemical : Dental Implants, Hypotonic Solutions.
- instrumentation : Plateletpheresis.
- methods : Platelet Transfusion, Plateletpheresis.
- surgery : Jaw, Jaw, Edentulous, Partially.
- Adult, Alveolar Ridge Augmentation, Blood Transfusion, Autologous, Cell Survival, Dental Implantation, Endosseous, Female, Humans, Male, Middle Aged, Platelet Activation, Platelet Aggregation, Platelet Count.
Abstract
A platelet concentrate, when combined with calcified thrombin, produces a platelet gel that has been used to achieve hemostasis and modulate bone growth and wound healing. The recovery of high concentrations of viable platelets and their resulting growth factor levels represents the most important factor in the clinical utility of a platelet concentrate because only functional platelets can release the growth factors that are necessary to induce tissue growth and bone regeneration. The SmartPReP system's efficiency in recovery of platelets from a sample of whole blood averaged 70.6%, almost twice that of various manual techniques using laboratory centrifuges. Platelet concentrates prepared by the SmartPReP system had a viability equal to platelet concentrates prepared for transfusion as measured by hypotonic stress, platelet aggregation, and p-selectin. A series of clinical case studies demonstrates the use of autologous platelet gel in oral surgery.
PubMed: 12704953
Affiliations:
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Le document en format XML
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Babbush</name><affiliation wicri:level="1"><nlm:affiliation>Dental Implant Center, Cleveland, OH, USA. implnt@buckeyeweb.com</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Dental Implant Center, Cleveland, OH</wicri:regionArea><wicri:noRegion>OH</wicri:noRegion></affiliation></author><author><name sortKey="Kevy, Sherwin V" sort="Kevy, Sherwin V" uniqKey="Kevy S" first="Sherwin V" last="Kevy">Sherwin V. Kevy</name></author><author><name sortKey="Jacobson, May S" sort="Jacobson, May S" uniqKey="Jacobson M" first="May S" last="Jacobson">May S. Jacobson</name></author></analytic><series><title level="j">Implant dentistry</title><idno type="ISSN">1056-6163</idno><imprint><date when="2003" type="published">2003</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Alveolar Ridge Augmentation</term><term>Blood Transfusion, Autologous</term><term>Cell Survival</term><term>Dental Implantation, Endosseous</term><term>Dental Implants</term><term>Female</term><term>Growth Substances (analysis)</term><term>Humans</term><term>Hypotonic Solutions</term><term>Jaw (surgery)</term><term>Jaw, Edentulous, Partially (surgery)</term><term>Male</term><term>Middle Aged</term><term>P-Selectin (analysis)</term><term>Platelet Activation</term><term>Platelet Aggregation</term><term>Platelet Count</term><term>Platelet Transfusion (methods)</term><term>Plateletpheresis (instrumentation)</term><term>Plateletpheresis (methods)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Activation plaquettaire</term><term>Adulte</term><term>Adulte d'âge moyen</term><term>Agrégation plaquettaire</term><term>Femelle</term><term>Humains</term><term>Implants dentaires</term><term>Mâchoire ()</term><term>Mâchoire partiellement édentée ()</term><term>Mâle</term><term>Numération des plaquettes</term><term>Pose d'implant dentaire endo-osseux</term><term>Reconstruction de crête alvéolaire</term><term>Solution hypotonique</term><term>Substances de croissance (analyse)</term><term>Survie cellulaire</term><term>Sélectine P (analyse)</term><term>Thrombocytaphérèse ()</term><term>Thrombocytaphérèse (instrumentation)</term><term>Transfusion de plaquettes ()</term><term>Transfusion sanguine autologue</term></keywords><keywords scheme="MESH" type="chemical" qualifier="analysis" xml:lang="en"><term>Growth Substances</term><term>P-Selectin</term></keywords><keywords scheme="MESH" type="chemical" xml:lang="en"><term>Dental Implants</term><term>Hypotonic Solutions</term></keywords><keywords scheme="MESH" qualifier="analyse" xml:lang="fr"><term>Substances de croissance</term><term>Sélectine P</term></keywords><keywords scheme="MESH" qualifier="instrumentation" xml:lang="en"><term>Plateletpheresis</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Platelet Transfusion</term><term>Plateletpheresis</term></keywords><keywords scheme="MESH" qualifier="surgery" xml:lang="en"><term>Jaw</term><term>Jaw, Edentulous, Partially</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Alveolar Ridge Augmentation</term><term>Blood Transfusion, Autologous</term><term>Cell Survival</term><term>Dental Implantation, Endosseous</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Platelet Activation</term><term>Platelet Aggregation</term><term>Platelet Count</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Activation plaquettaire</term><term>Adulte</term><term>Adulte d'âge moyen</term><term>Agrégation plaquettaire</term><term>Femelle</term><term>Humains</term><term>Implants dentaires</term><term>Mâchoire</term><term>Mâchoire partiellement édentée</term><term>Mâle</term><term>Numération des plaquettes</term><term>Pose d'implant dentaire endo-osseux</term><term>Reconstruction de crête alvéolaire</term><term>Solution hypotonique</term><term>Survie cellulaire</term><term>Thrombocytaphérèse</term><term>Transfusion de plaquettes</term><term>Transfusion sanguine autologue</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">A platelet concentrate, when combined with calcified thrombin, produces a platelet gel that has been used to achieve hemostasis and modulate bone growth and wound healing. The recovery of high concentrations of viable platelets and their resulting growth factor levels represents the most important factor in the clinical utility of a platelet concentrate because only functional platelets can release the growth factors that are necessary to induce tissue growth and bone regeneration. The SmartPReP system's efficiency in recovery of platelets from a sample of whole blood averaged 70.6%, almost twice that of various manual techniques using laboratory centrifuges. Platelet concentrates prepared by the SmartPReP system had a viability equal to platelet concentrates prepared for transfusion as measured by hypotonic stress, platelet aggregation, and p-selectin. A series of clinical case studies demonstrates the use of autologous platelet gel in oral surgery.</div></front></TEI><affiliations><list><country><li>États-Unis</li></country></list><tree><noCountry><name sortKey="Jacobson, May S" sort="Jacobson, May S" uniqKey="Jacobson M" first="May S" last="Jacobson">May S. Jacobson</name><name sortKey="Kevy, Sherwin V" sort="Kevy, Sherwin V" uniqKey="Kevy S" first="Sherwin V" last="Kevy">Sherwin V. Kevy</name></noCountry><country name="États-Unis"><noRegion><name sortKey="Babbush, Charles A" sort="Babbush, Charles A" uniqKey="Babbush C" first="Charles A" last="Babbush">Charles A. Babbush</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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